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Intravenous NAD⁺: What It Is, What It Isn’t, and When It May Be Appropriate

Nicotinamide adenine dinucleotide (NAD⁺) has garnered considerable attention in recent years as a potential therapeutic agent in various clinical and wellness contexts. Its role in cellular metabolism and energy production has prompted interest in its application for ageing, fatigue, neurocognitive disorders, and recovery from illness or injury. However, the distinction between biological plausibility and clinical efficacy remains critical, particularly when considering intravenous administration. This article aims to provide a clinically grounded, evidence-aware overview of intravenous NAD⁺ therapy, elucidating its physiological basis, administration nuances, patient selection criteria, and risk management considerations.

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